Respiratory Allergic Diseases

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Journal of Allergy & Therapy is a peer-reviewed journal covers a broad spectrum of topics, including allergy, allergic rhinitis, asthma, drug allergies, atopic dermatitis, clinical immunology, hypersensitivity, saliva allergy, reactive airways dysfunction syndrome, irritant-induced asthma, reactive attachment disorder (RADS) syndrome, oil and vitamin-associated inflammation, allergy-associated skin tests and their interpretation, allergy test results scale, ethanol-associated allergy, chronic obstructive pulmonary disease, and more.

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Due to their negative effects on quality of life, including social interaction, school attendance, and job performance, allergic airway diseases, such as Bronchial Asthma (BA) and Allergic Rhinoconjunctivitis (AR), are significant health and economic burdens. Allergy-related airway illnesses can arise for a variety of reasons, including genetic and environmental influences. Pollen is a significant environmental element that can lead to respiratory allergies. A distinctive feature of pollinosis is a country-specific, recurrent pattern of symptoms that occur during the pollen season. The symptoms of respiratory allergies are present year-round in patients who are sensitive to both seasonal (such as pollen) and perennial allergens (such as House Dust Mites (HDM), cockroaches, and moulds) and are exacerbated during the pollen season. The pollen season and the flowering season are related, but air pollution and climate change are the primary factors affecting pollen allergenicity. Pollution increases the amount of pollen allergenic proteins, particularly in metropolitan regions, and modifies these proteins into more allergenic components that cause allergies in susceptible people. On the other hand, the timing, length, geographic range, and dispersion of the pollen season are all impacted by climate change. Most pollen allergies come from grasses, weeds, and trees. 40% of pollen sensitivity is brought on by grass pollen because of its prolific production and widespread dissemination. Numerous studies conducted in the United States revealed that grass pollen was primarily to blame for summer visits, whereas tree pollen was the cause of 25,000-50,000 hospital admissions for asthma throughout the spring. Weeds, on the other hand, are more common in the fall. The primary weeds that produce weed pollen on a global scale are parietaria, ragweed, mugwort, sunflower, and Russian thistle. Oral allergy syndrome develops in people who have previously been sensitive to aeroallergens and plant-derived allergens. Oral Allergy Syndrome (OAS), an acute hypersensitivity reaction, causes itching of the lips, tongue, and throat when raw fruits or vegetables come into contact with the oral mucosa. In 2%-10% of instances, OAS may be accompanied by more serious symptoms including angioedema or anaphylaxis. Profiling, pathogenesis-related protein 10, and lipid transfer proteins are the key allergenic factors in OAS. Skin Prick Tests (SPT) and/or the detection of serum IgE in entire allergen extracts have historically been used to support patient anamnesis in the diagnosis of allergic disorders. Both approaches are effective at identifying reactivity to allergen extracts, but they are unable to pinpoint the precise components that cause sickness.